High throughput bioreactor is a process that can be clearly observed during the fermentation operation of bacterial strains in metabolic fermentation tankspHChanges in values and other parameters (such as bacterial growthOUR、CER、RQVarious replenishment operations…The correlation between different fermentation times can reflect changes in the physiological state of bacterial cells, which is of great significance for optimizing and scaling up the fermentation process. beltpHThe high-throughput bioreactor for measurement not only overcomes the difficulty of multi parameter measurement in shake flasks, but also serves as a fundamental principle for metabolic flow analysis. grasppHThe combination of real-time measurement and flow addition technology is of great significance for achieving dynamic research with metabolic flow as the core.
Due to the use of multiple shaking bottles and the combination control operation of different processes, the research progress can be greatly shortened.
2、 Excellentdrop
1、pHReal time changes can cause changes in the physiological characteristics of bacterial strains,pHThe detection function provides strong evidence for metabolic flow analysis
2Carefully designed micro replenishment technology andpHThe combination of real-time detection and stream addition technology is of great significance for achieving dynamic research with metabolic flow as the core
3The control operation of multi-channel shaking bottles and various combinations of processes can greatly shorten the progress of process research
3、 Application:
1. Process of bacterial growthpHResearch on the Variation Pattern, Vaccination Volume, and Transfer Timing of Seeds
2. Optimization of Basic Culture Medium
3. The optimal stages for bacterial growth and hormone productionpHresearch on
4. Research on flow additive feeding, including feeding types, rates, and kinetics studies
5. Dynamic research centered on modern metabolic flow can be implemented.
4、 System composition
component |
quantity |
10Inch touch screen host |
1tower |
500ml(Or1000ml)High borosilicate glass cultivation tank |
8only |
pHElectrode(Import) |
8root |
pHAcid alkali flow with peristaltic pump |
8only |
Ultra micro feeding control peristaltic pump |
8only |
Siemens GermanyPLCcontroller |
1cover |
refrigeration+Heating automatic temperature control system |
1cover |
Rotameter(air/Pure oxygen ratio mixing) |
2individual |
5、 Technical indicators:
name call |
TECHNICAL INDEX |
Component configuration and description |
|
Chassis size |
850*620*1355(mm) |
Professional Design |
|
Shake board size |
760*460(mm) |
SUS316L |
|
Temperature controller (heating+refrigeration) |
selfControl range:10℃-50℃ Accuracy: ±0.2℃ |
Sensor:PT100(Imported platinum resistance) Temperature transmitter(Good-shine) |
|
Speed control system |
Control range:0~280rpm Control accuracy: ±2% |
electric machinery:0.2KWDC servo motorThe speed is infinitely adjustable; Optoelectronic testing; Low noise, low vibration DC speed control board(Good-shine) |
|
pHcontrol system |
Control range:2.00-12.00 Control accuracy:±0.02 |
High temperature resistant sterilizationpHElectrode, wire Peristaltic pump (programmable precision peristaltic pump) |
|
Ultra micro replenishment control |
Range:0.2ml~200ml/min Accuracy:± 0.02ml |
Peristaltic pump (programmable precision peristaltic pump) Can be withpHRelated control |
|
GasMi(Air+O2)Mixed ventilation |
Range:1~20L/ min Accuracy:±5% |
Rotameter Filter: Sartorius Specialized ventilation valve |
|
hardware |
Adopting Siemens from GermanyPLCAs the core control unit, it operates stably and reliably; Easy to operate, user-friendly, and each channel can store30000Click on historical data. |